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Innovative electroporation device, which enables completely new research in the field of electroporation

Summary

Profile Type
  • Technology offer
POD Reference
TOSI20230320003
Term of Validity
14 April 2023 - 13 April 2025
Company's Country
  • Slovenia
Type of partnership
  • Investment agreement
Targeted Countries
  • All countries
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General information

Short Summary
The invention encompasess electroporation device, which enables completely new research in the field of electroporation and can be upscaled into medical device.
Full Description
Electroporation is a s promising technology for cancer and cardiac arrhythmia treatment and an efficient DNA delivery method. Among the most promising gene electrotransfer applications in medicine are DNA vaccination and gene therapy. It works like this: When we expose cells to high voltage electric pulses, we increase the permeability of the cell membrane. So, molecules which otherwise cannot enter the membrane, now can penetrate in to cell interior. By using more pulses or increasing pulse voltage, we can also kill cells or ablate tissue. The device that generates electroporation pulses is called electroporator. And this technology develops electroporators. But the problem is that medical electroporators available on the market, use long monopolar pulses that are painful, but the company was the first to show that high-frequency bipolar pulses cause significantly less pain.Therefore their technology is both effective and more patient-friendly.

The company's first product is a laboratory high-frequency electroporator. This is the device that you need if you want to research electroporation in vivo or in vitro. The product is the only electroporator on the market that enables generation of high-frequency bipolar electroporation pulses on the entire scale of high-frequency electroporation. User interface was developed in the collaboration with the researches, meaning it is extremely flexible. The user can set up to 9 pulse parameters while at competitive laboratory electroporator you can mainly set up to 4. So, this device enables completely new research in the field of electroporation. Since the first prototype the devices has been used at the Institute of Oncology in Ljubljana and at the University of Ljubljana. Up to date, the research team has managed to demonstrate the useful value of it in as many as fifteen biomedical research studies. In the first phase, the company is marketing the laboratory electroporator because such certification is less demanding and, of course, cheaper. However, in the future, the company will also upgrade the device for use in veterinary medicine. In the case of acquiring a major investment, the company will also certify the device as a medical electroporator.
Advantages and Innovations
The product is the only electroporator on the market that enables generation of high-frequency bipolar electroporation pulses on the entire scale of high-frequency electroporation.
Stage of Development
  • Already on the market
Sustainable Development Goals
  • Goal 3: Good Health and Well-being
IPR status
  • Secret know-how

Partner Sought

Expected Role of a Partner
The company is open to partners with the experiences in putting a medical device to market. Mainly it is looking for experts in the field of medical device certification.
Type and Size of Partner
  • SME 11-49
  • Big company
  • SME <=10
  • SME 50 - 249
Type of partnership
  • Investment agreement

Dissemination

Technology keywords
  • 006001012 - Electromedical and Medical Equipment
Market keywords
  • 05004001 - Electromedical and medical equipment
Targeted countries
  • All countries