A Custom Development and Manufacturing Organization (CDMO) based on experience, trust and quality, which delivers commercial-scale solutions to biotech and chemical start-ups´ and SMEs´ challenges

Summary

Profile Type

Business Offer

POD Reference

BOCZ20230223007

Term of Validity

23 February 2023 - 22 February 2025

Company's Country

Czechia

Type of partnership

Commercial agreement

Targeted Countries

All countries

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General information

Short Summary

With > 120 years of experience, the company offers a complete set of services for the commercial-scale production of product, via its fermentation CDMO assets. Whether started for a lab experiment or from a developed process, inventions will reach market in a limited amount time and with the appropriate quality standards. Companies looking for a partner who understands, a supplier who performs, and an innovator who goes beyond, the company might the right one to partner with.

Full Description

Following the boom of biotechnology which started about 20 years ago, SMEs and start-ups are an incredible source of new inventions that are now reaching enough maturity, and therefore require production capacities. The need for capacities as per se goes alongside the need for experienced large-scale manufacturers in the fermentation field, that can accompany these SMEs and start-ups towards commercial launch. If finding the right partner is the fermentation hot topic of the moment, the company with its long-standing experience in the field and with a Swiss base, it is devoted to support its collaborators in this race to market.

From concept to manufacturing, the company is following a stepwise approach in order to maximize success day after day. Whether the project requires further development in the lab or is ready to be transferred in commercial assets, the company´s team will design the relevant customized strategy to support its partner’s successes.

Thanks to its two CDMO sites, the company is also uniquely offering the possibility to produce via a mixed of chemistry and biotechnology, when it is adding value to a project.

Company snapshot:

- R&D, Pilot and Manufacturing (up to multi metric tons).
- Exclusive manufacturing of small / large molecules, proteins, enzymes, … for advanced
intermediates and active ingredients.
- Several quality standards (ISO9001, FSSC22000 / HACCP, FAMI QS, Halal, Kosher, …).
- Active in various market (food, feed, cosmetics, agro, …)
- Experienced teams.
- > 50 processes successfully transferred to industrial scale within the last 10 years.

Biotech roadmap:
- Fermentation development
o Fermentation and media optimization (DoE)
o Scale-down studies
o Selection and definition of process control parameters

- Down Stream Processing (DSP), Analytics, Formulation
o DSP development and optimization
o Analytical development (in-process and final product)
o Formulation development (focus on product stability)

- Scale-up and Tech transfer
o Process and analytics validation
o Equipment selection for best fit to manufacturing
o Scale-up criteria definition for industrial tech. transfer

- Manufacturing
o Commercial manufacturing
o Continuous process optimization
o Registration support

Capabilities
- 5 independent lines with fermenters
- Total volume: 475 m3
- Fermenter volumes: 15-75 m3 (up to 250 m3 per line)
- Pilot line: 1,5 m3
- Quantities: 1 – 100 tons
- Highly versatile DSP.
- Ex-proof equipment and BSL-2 handling (some lines).
- Integrated waste management.

Advantages and Innovations

- Strategic partner.
- Tailored project.
- Collaborative approach to reach target.
- Teams of skilful experts

Sustainable Development Goals

Goal 2: Zero Hunger
Goal 12: Responsible Consumption and Production

Partner Sought

Expected Role of a Partner

The company is offering its CDMO services to start-ups and SMEs that are looking for an experienced manufacturing partner in the biotechnological / high precision fermentation field, within various market (food, feed, cosmetics, agro, …).

Type and Size of Partner